Aptamers: Update to Lateral Flow Immunoassays
نویسندگان
چکیده
منابع مشابه
Analytical sensitivity limits for lateral flow immunoassays.
A plethora of literature describes the use of lateral flow immunoassays (LFIA). Only a fraction of that contains information about possible analytical sensitivity or limit of detection. Accordingly, we have undertaken a comprehensive survey of the literature in PubMed and present here that fraction that has information on limits of detection or analytical sensitivity. Further detail of the sear...
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Lateral flow immunoassays (LFIA) are ideal biosensors to detect proteins, but their lack of sensitivity hinders their extensive use. We report a strategy that yields up to an 8-fold improvement in the sensitivity of a gold nanoparticles-based LFIA by changing the sizes of the pads. Theoretical flow simulations of the developed LFIA architectures are in accordance with the experimental results.
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Shiga toxin-producing Escherichia coli O157:H7 (STEC) cause food-borne illness that may be fatal. STEC strains enumerate two types of potent Shiga toxins (Stx1 and Stx2) that are responsible for causing diseases. It is important to detect the E. coli O157 and Shiga toxins in food to prevent outbreak of diseases. We describe the development of two multi-analyte antibody-based lateral flow immuno...
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There is an increasing demand for convenient and accurate point-of-care tools that can detect and diagnose different stages of a disease in remote or impoverished settings. In recent years, lateral flow immunoassays (LFIA) have been indicated as a suitable medical diagnostic tool for these environments because they require little or no sample preparation, provide rapid and reliable results with...
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ژورنال
عنوان ژورنال: Current Trends in Biomedical Engineering & Biosciences
سال: 2017
ISSN: 2572-1151
DOI: 10.19080/ctbeb.2017.09.555773